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SparkSpine™: Neuroregenerative Scaffold System via Bio-Routed Fungal Pathways

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DataCite Commons2025-06-04 更新2025-09-08 收录
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SparkSpine™: Neuroregenerative Scaffold System via Bio-Routed Fungal PathwaysSparkSpine™ is an advanced, bioelectronic scaffold system designed to revolutionize spinal cord injury repair. Integrating dynamic bio-guided fungal growth with conductive hydrogel and programmable SPARC field modulation, SparkSpine™ creates a real-time adaptive pathway for nerve regeneration.This entry includes:<br>Executive SummaryMarket AnalysisMVP Development BlueprintBill of Materials (BOM)Risk AssessmentSuccess MetricsKey Highlights:<br>Utilizes Physarum polycephalum or synthetic analogs in DestinyGel™ hydrogel to map least-resistance regenerative pathways.Incorporates embedded gold/silver microfibers and graphene for electrical conductivity.Features programmable SPARC fields (0.1–10 Hz) to promote neurite outgrowth and enhance signal conduction.Supports &gt;40% increase in neurite outgrowth in vitro, with &gt;90% cell viability.MVP prototype BOM totals $46,760 with full MVP budget of $376,074.SparkSpine™ represents a transformative leap in regenerative medicine—positioning itself as the first adaptive bioelectronic neural scaffold with clinical translation potential.<br>

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figshare
创建时间:
2025-06-04
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