Supplementary Material for: Increased Focus on Internal Body Sensations Is Associated with Higher Patient-Perceived Severity of Allergic Rhinitis

<b><i>Background:</i></b> Monitoring allergic rhinitis (AR) severity with objective biomarkers is important for the clinical management of patients as well as for research purposes. The most commonly used tool for the assessment of AR severity is the Total Nasal Symptom Score (TNSS). Objective biomarkers like skin prick test size or specific IgE levels do not correlate with TNSS. <b><i>Objective:</i></b> We hypothesize that the psychological factors are the missing link between patient-perceived severity of AR and objective biomarkers. <b><i>Method:</i></b> Thirty-nine patients (median age: 34 years; 21 [54%] female) with grass pollen-related AR were enrolled in our study. Patients allergic for perennial allergens and allergens with potentially overlapping seasons including cypress, ash/olive, plane, and nettle families were excluded. Patient-reported outcomes included symptom score, medication scores, combined score, and Juniper Mini Rhinitis Quality of Life Questionnaire (minRQLQ). Psychometric evaluation was performed using 5 different psychological questionnaires that measure 13 different psychological factors. <b><i>Results:</i></b> There was a significant correlation between the symptom score and <i>private body consciousness</i> (<i>r</i> = 0.50, <i>p</i> = 0.001) and <i>neuroticism</i> (<i>R</i> = 0.41 and <i>p</i> = 0.01). There was also a statistically significant correlation between the combined score and <i>private body</i> consciousness (<i>r</i> = 0.49 and <i>p</i> = 0.001) and with <i>perceiving and understanding emotions</i> (<i>r</i> = 0.34 and <i>p</i> = 0.04). The miniRQLQ score had a positive correlation with <i>private body consciousness</i> (<i>r</i> = 0.55 and <i>p</i> = 0.002) and <i>observing</i> (<i>r</i> = 0.42 and <i>p</i> = 0.02). <b><i>Conclusions:</i></b> Our data suggest that patients who are more aware of internal stimuli, as well as those who are highly self-conscious and somatically concerned tend to experience more severe AR symptoms.