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MYDGF Governs Endothelial Homeostasis in Hypertension

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP599648
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资源简介:
Myeloid-derived growth factor (MYDGF) demonstrates well-established cardioprotective properties. However, its endothelial-specific functions and potential therapeutic applications in hypertension remain largely unexplored. Through comparative RNA sequencing analysis of Ang II-treated endothelial cells with versus without MYDGF overexpression, we identified genes associated with endothelial functional modulation. Overall design: The gene expression of 5 samples from 48 h Ang II induced AD-MYDGF endothelial cell line was compared to 5 samples from 48 h Ang II induced AD-NC samples by RNA sequencing.
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2025-07-14
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