11DCORST translocates from cytosol to mitochondrial matrix

11-deoxycorticosterone is synthesized in a reaction at the endoplasmic reticulum membrane and is further metabolized, ultimately to yield aldosterone, in reactions catalyzed by mitochondrial enzymes. The means by which 11-deoxycorticosterone translocates into the mitochondrial matrix, however, is unknown.

11-脱氧皮质酮在粗面内质网膜的反应中合成，随后在由线粒体酶催化的反应中进一步代谢，最终生成醛固酮。然而，11-脱氧皮质酮如何转运进入线粒体基质的方式尚属未知。