首页/数据集/A human tissue screen identifies a regulator of ER secretion as a brain size determinant [scRNA-Seq]. A human tissue screen identifies a regulator of ER secretion as a brain size determinant [scRNA-Seq]

A human tissue screen identifies a regulator of ER secretion as a brain size determinant [scRNA-Seq]. A human tissue screen identifies a regulator of ER secretion as a brain size determinant [scRNA-Seq]

NIAID Data Ecosystem2026-03-11 收录

类器官单细胞转录组

脑尺寸调控机制

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA635648 数据链接链接失效反馈

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资源简介：

A screen in human organoids reveals IER3IP1 function Overall design: scRNAseq of organoids, day40, 10x Chromium

应用场景：

创建时间：

2020-05-28

类器官单细胞转录组

干细胞研究

Here, we used single-nuclei RNA-sequencing (snRNA-seq) to profile pluripotent stem cell-derived human intestinal organoids (HIOs) grown in media comprised of minigut media + 10 ng/ml EREG in vitro for

NIAID Data Ecosystem100

Engineering a Brain Parasite for Intracellular Delivery of Proteins to the Central Nervous System

中枢神经系统蛋白质递送

类器官单细胞转录组

Delivering macromolecules across biological barriers such as the blood-brain-barrier limits their application in vivo. Here we show that Toxoplasma gondii, a parasite that naturally travels from the h

NIAID Data Ecosystem70

Single-cell transcriptome of cerebral organoids with and without methanol fixation

甲醇固定效应

类器官单细胞转录组

To study how methanol fixation affects single-cell transcriptomic measurement, two cerebral organoids were dissociated. Cell suspension of each organoid was split into two aliquots. Methanol fixation

NIAID Data Ecosystem50

Single-Cell RNA Sequencing Analysis of Intestinal organoids expanded in either IntestiCult™ Plus or IntestiCult™ OGM (Human)

类器官单细胞转录组

培养基优化

Conventional Intestinal organoids such as those supported by IntestiCult™ Organoid Growth medium (Human) often fail to recapitulate the cellular diversity of the intestinal epithelium and are typicall

NIAID Data Ecosystem70

Histological and single cell transcriptomic analysis of human retinal organoid models of Leber Congenital Amaurosis identifies endoplasmic reticulum stress as a common degenerative pathway. Histological and single cell transcriptomic analysis of human retinal organoid models of Leber Congenital Amaurosis identifies endoplasmic reticulum stress as a common degenerative pathway

遗传性视网膜疾病内质网应激

类器官单细胞转录组

This study utilized human stem cell derived retinal organoids to characterize two models of Leber Congenital Amaurosis. Using CRISPR/Cas9, we generated CRB1 and RPGRIP1 KO cell lines and differentiate

NIAID Data Ecosystem60

A human tissue screen identifies a regulator of ER secretion as a brain size determinant [scRNA-Seq]. A human tissue screen identifies a regulator of ER secretion as a brain size determinant [scRNA-Seq]

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