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A specific prelimbic-nucleus accumbens pathway controls resilience versus vulnerability to develop food addiction.

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The aim of this study was to analyse the whole transcriptome profile of medial prefrontal cortex of food addicted and non-addicted Glu-CB1-WT and Glu-CB1-KO mice using total RNA-seq. mPFC RNA was isolated of food addicted and non-addicted Glu-CB1-WT and Glu-CB1-KO mice, total RNA was rRNA depleted, and RNA sequencing was done on a Illumina NextSeq 500 sequencer.

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