Identify urinary exosome microRNAs that are unique to premature ovarian insufficiency

This study is to identify urinary exosome microRNAs (miRNAs) that are unique to premature ovarian insufficiency (POI) with and without Turner syndrome and to use them as diagnostic markers for POI patients. We examined the miRNAexpression profile in urine exosomes from POI patients with and without Turner syndrome. Overall design: We analyzed the miRNA expression profile isolated from the urinary exosomes of POI patients with or without Turner syndrome.