Transcriptomic RNA-seq analysis of single- or co-infected with PCV2 and PRV on the PK-15 cells for 12 and 36 h

In this study transcriptomic RNA-seq analysis was performed on cells single- or co-infected with PCV2 and PRV for 12 and 36 h. Compared with the control group (PK-15), a total of 5143 differentially expressed genes (DEGs) were identified in PCV2 infected cells (2399 up-regulated genes and 2744 down-regulated genes), a total of 4122 DEGs were identified in PRV infected cells (1970 up-regulated genes and 2152 down-regulated genes), and a total of 4825 DEGs were identified in PCV2 infected cells (2199 up-regulated genes and 2626 down-regulated genes) Furthermore, a total of 3218 shared DEGs were identified in three infection groups via a Venn diagram.