Metagenomic next-generation sequencing detect the tumor cells

mNGS has the potential to further improve diagnosis of lung cancer in patients with pneumonic-type lung cancer. First, it is of high sensitivity and high throughput for nucleic-acid sequencing. Second, mNGS could warn of cancer by detecting the chromosomal instability of exfoliated tumor cells of alveolar lavage fluid from patients whose samples cannot be collected using existing sampling tools in bronchioli.