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Cryo-EM structure of the rat P2X7 receptor in the apo closed state

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Protein Data Bank Japan2025-05-14 更新2026-05-23 收录
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Cryo-EM structure of the rat P2X7 receptor in the apo closed state Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GUANOSINE-5'-DIPHOSPHATE, P2X purinoceptor 7, ... Authors: Oken, A.C, Lisi, N.E, Krishnamurthy, I, McCarthy, A.E, Godsey, M.H, Glasfeld, A, Mansoor, S.E. Deposit date: 2023-08-09 Release date: 2024-08-14 Last modified: 2025-05-14 Method: ELECTRON MICROSCOPY (2.53 Å) Cite: High-affinity agonism at the P2X 7 receptor is mediated by three residues outside the orthosteric pocket. Nat Commun, 15, 2024

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2023-08-09
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