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Astrocyte Panel - Images
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创建时间：
2025-03-31
相关数据集
Region specific astrocyte response to mutant GFAP in Alexander disease model mice during postnatal development.. Region specific astrocyte response to mutant GFAP in Alexander disease model mice during postnatal development.
Gene expression analysis was performed in Gfap+/+, Gfap+/R236H, and mGFAPTg170-2 transgenic mice, using the Aldh1l1-eGFP-L10a transgenic line (JD130) to isolate translating ribosomes and purify astroc
NIAID Data Ecosystem70
Transcriptomic profile of reactive astrocytes induced by activation of the JAK2-STAT3 pathway in mouse striatal astrocytes. Transcriptomic profile of reactive astrocytes induced by activation of the JAK2-STAT3 pathway in mouse striatal astrocytes
We analyzed the transcriptional profile of normal astrocytes and astrocytes made reactive by AAV gene transfer of a contitutive form of JAK2 (JAK2ca). We show that activation of the JAK2-STAT3 pathway
NIAID Data Ecosystem20
A phenotypic screening platform for identifying chemical modulators of astrocyte reactivity [scRNAseq]. A phenotypic screening platform for identifying chemical modulators of astrocyte reactivity [scRNAseq]
Disease, injury, and aging induce pathological reactive astrocyte states that contribute to neurodegeneration. Modulating reactive astrocytes therefore represents an attractive therapeutic strategy. H
NIAID Data Ecosystem20
CROP-seq of hiPSC-derived astrocytes (bulk RNA-Seq)
In response to central nervous system injury or disease, astrocytes become reactive, adopting context-dependent states with altered functions. Certain inflammatory insults induce reactive astrocyte st
NIAID Data Ecosystem50
The swith off/on genes in A0 astrocyte to A1/A2 astrocyte of mouse. Mus musculus
Primary astrocyte of mouse brain was used as the cell line model for A0 astrocyte change to A1/A2 astrocyte. Bulk RNA-seq of the A0 astrocyte, A1 astrocyte and A2 astrocyte were produced. By integrati
NIAID Data Ecosystem20
