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Down-regulation of Interferon signature in systemic lupus erythematosus patients by active immunization with Interferon alpha-Kinoid

ChEBI2012-11-01 更新2026-07-21 收录

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干扰素特征调节

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-39088 数据链接链接失效反馈

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Down-regulation of Interferon signature in systemic lupus erythematosus patients by active immunization with Interferon alpha-Kinoid

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创建时间：

2012-11-01

调节性T细胞功能

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The therapeutic use of regulatory T cells (Tregs) in patients with autoimmune disorders has been hampered by the biological variability of memory Treg populations in the peripheral blood. In this stud

NIAID Data Ecosystem60

Table_7_Uncovering lupus nephritis-specific genes and the potential of TNFRSF17-targeted immunotherapy: a high-throughput sequencing study.xlsx

狼疮性肾炎分子靶点

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IntroductionLupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus (SLE). This study aimed to identify LN specific-genes and potential therapeutic targets. MethodsWe performed

NIAID Data Ecosystem10

Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell activator.

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NKT细胞激活研究

Injection of the glycolipid alpha-GalCer (20:2) reduced the percentage of iNKT cells, stained with CD1d/epitope tetramers, at 1 to 30 wk post-injection in the spleen and and at 5-30 wk in peripheral l

ImmuneData10

Butyrate-modified liposomes target the delivery of itaconic acid to modulate the Th17/Treg cell balance through epigenetic reprogramming, improving primary biliary cholangitis

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纳米药物递送

Primary biliary cholangitis (PBC) is a chronic autoimmune disease. This study aims to design itaconic acid (IA)-loaded butyrate (Bu)-modified lipid nanoparticles (LNP-Bu@IA) for targeted delivery of I

NIAID Data Ecosystem10

A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis

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mRNA疫苗耐受诱导

The ability to control autoreactive T cells without inducing systemic immune suppression is the major goal for treatment of autoimmune diseases. The key challenge is the safe and efficient delivery of

NIAID Data Ecosystem10

Down-regulation of Interferon signature in systemic lupus erythematosus patients by active immunization with Interferon alpha-Kinoid

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