Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6

The human SLC5A11 gene encodes a high affinity myo-inositol transporter (SMIT2, SGLT6) (Ostlund RE et al, 1996; Roll P et al, 2002). It can transport myo-inositol and D-chiro-inositol, together with two Na+ ions. It was thought SGLT6 could transport glucose but there is no evidence for this so far (Lin X et al, 2009).

人类 SLC5A11 基因编码一种高亲和力肌醇转运蛋白（SMIT2，SGLT6）（Ostlund RE 等，1996；Roll P 等，2002）。该转运蛋白能够运输肌醇和 D-赤藓醇肌醇，并伴随两个钠离子一同进行。曾认为 SGLT6 可运输葡萄糖，然而迄今为止尚无确凿证据（Lin X 等，2009）。