Transcriptome in granulosa layer of masu salmon Oncorhynchus masou. Oncorhynchus masou masou

The maturation-inducing hormone 17a,20b-dihydroxy-4-pregnen-3-one (DHP) was first identified in the amago salmon. However, although carbonyl reductase-like 20b-hydroxysteroid dehydrogenase (CR/20b-HSD) was reported to convert 17a-hydroxyprogesterone (17a-P) to DHP in rainbow trout, we previously found that CR/20b-HSD mRNA was not up-regulated in stimulated granulosa cells from masu salmon, which suggests that DHP is synthesized by a different enzyme. Accordingly, the BioProject aimed to identify the specific 20b-hydroxysteroid dehydrogenase (20b-HSD) responsible for DHP production by granulosa cells during final oocyte maturation in masu salmon.