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A Tyrosine Reactive Cross-Linker for Probing Protein 3D Structures

Name: A Tyrosine Reactive Cross-Linker for Probing Protein 3D Structures
Creator: Jilin University&National Institute of Metrology
Published: 2020-10-22T10:18:37+08:00

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蛋白质结构探测

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数据链接：

https://www.iprox.cn/page/project.html?id=IPX0002539000 数据链接链接失效反馈

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资源简介：

A Tyrosine Reactive Cross-Linker for Probing Protein 3D Structures

应用场景：

提供机构：

Jilin University&National Institute of Metrology

创建时间：

2020-10-22

交联质谱

数据独立采集

Cross-linking Mass Spectrometry (XL-MS) is a powerful tool for examining protein structures and interactions. Nevertheless, anal-ysis of low-abundance cross-linked peptides is often limited in data-de

国家人口健康科学数据中心120

Reanalysis of a synthetic cross-linked peptide library with MaxLynx

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蛋白质相互作用

Reanalysis of a synthetic crosslinked peptide library datasets with DSS (non-cleavable), DSSO and DSBU (MS-cleavable) cross linkers from Beveridge et al., Nat. Commun., 2020 (PXD014337)

NIAID Data Ecosystem50

DSBSO-based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples

癌症蛋白质相互作用

交联质谱

We applied our previously established Alkyne-A-DSBSO-based in vivo XL-MS analytical platform on two types of breast cancer PDX samples cross-linking. Coupled with the LC-MSn strategy, the experiments

NIAID Data Ecosystem20

Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome

蛋白质复合物结构解析

交联质谱

The 26S proteasome is the macromolecular machine responsible for ATP/ubiquitin dependent degradation. As aberration in proteasomal degradation has been implicated in many human diseases, structural an

NIAID Data Ecosystem60

Peptide centric detection of cross-linked peptides using PASEF, MeroX, and Skyline

蛋白质相互作用

交联质谱

Cross-linking mass spectrometry (XL-MS) has evolved into a pivotal technique for probing protein interactions, with recent ad-vancements significantly enhancing its analytical potential. This technica

NIAID Data Ecosystem20

A Tyrosine Reactive Cross-Linker for Probing Protein 3D Structures

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