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AK104 in Locally Advanced MSI-H/dMMR Gastric Carcinoma and Colorectal Cancer

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下载链接:
https://www.omicsdi.org/dataset/ecrin-mdr-crc/2352126
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This is a single-arm, multicenter phase II clinical study. The aim is to evaluate the safety, tolerability, and anti-tumor activities of AK104(a PD-1/CTLA-4 bispecific antibody) in MSI-H/dMMR locally advanced gastric adenocarcinoma and colorectal cancer during the perioperative period.Eligible patients will receive AK104 for three cycles before surgery and at most 6 months after surgery. The primary endpoint is the pathological complete response rate.
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2020-10-15
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