Molar ratios of calculated opioid-specific IgG binding sites to the administered heroin dose.

IgG binding site concentrations are the means for all vaccinated rats in that experiment. Doses listed for the HSA studies are the mean total heroin intake over the 2-hr self-administration session. Doses listed for the drug distribution studies are the total amount of heroin administered over the 1-hr experiment.1Last three HSA sessions at 0.06 mg/kg/inf heroin during FR3.2s.c. administration, all other heroin doses administered i.v.Molar ratios of calculated opioid-specific IgG binding sites to the administered heroin dose.