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Senataxin associates with replication forks to protect fork integrity across RNAPII transcribed genes

ChEBI2012-11-09 更新2026-07-21 收录

DNA复制叉

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数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-39139 数据链接链接失效反馈

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资源简介：

Senataxin associates with replication forks to protect fork integrity across RNAPII transcribed genes

应用场景：

创建时间：

2012-11-09

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R-loop解析机制

Fine-tuning DNA replication and transcription is crucial to prevent collisions between their machineries. This is particularly important near promoters, where RNA polymerase II (RNAPII) initiates tran

NIAID Data Ecosystem70

FANCD2, FANCJ and BRCA2 cooperate to promote replication fork recovery independently of the Fanconi Anemia core complex

DNA复制叉

范可尼贫血通路

Fanconi Anemia (FA) is an inherited multi-gene cancer predisposition syndrome that is characterized on the cellular level by a hypersensitivity to DNA interstrand crosslinks (ICLs). To repair these le

Figshare2016-01-19 更新40

ChIP-chip data of Thp1-Flag and Sac3-Flag in wild-type cells, and Rrm3-Flag in sac3__ and thp1__ cells

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基因组不稳定性

Transcription is a major obstacle for replication fork progression and a cause of genome instability

Alliance of Genome Resources30

Strand break-induced replication fork collapse leads to C-circles, C-overhangs and telomeric recombination

端粒替代延长

DNA复制叉

Telomerase-independent ALT (alternative lengthening of telomeres) cells are characterized by high frequency of telomeric homologous recombination (HR), C-rich extrachromosomal circles (C-circles) and

Figshare2019-02-20 更新60

Nuclear functions of CFAP20 in transcription and replication [DRIP-seq]

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R-loop解析

Fine-tuning DNA replication and transcription co-occurrence is vital to avoid collisions between their machineries. This is especially relevant near promoters, where RNAPII initiates transcription and

NIAID Data Ecosystem30

Senataxin associates with replication forks to protect fork integrity across RNAPII transcribed genes

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