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Systems biology approaches to explore cyclic stretching in cardiac cell physiology

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NIAID Data Ecosystem2026-03-11 收录
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Mechanical forces are involved in pressure-overloaded cardiomyopathy. However, the transcriptional profile related to mechanical loading in cardiomyocytes is still not fully understood. Here, we investigated the genomic profile of stretched human cardiomyocytes using next-generation sequencing (NGS). Results showed that 85, 87, 32, 29, and 28 genes were differentially expressed after 1, 4, 12, 24, and 48 hours of stretching.

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2020-03-16
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