A Cycloisomerization/Friedel–Crafts Alkylation Strategy for the Synthesis of Pyrano[3,4-b]indoles
收藏Figshare2016-02-23 更新2026-04-29 收录
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https://figshare.com/articles/dataset/A_Cycloisomerization_Friedel_Crafts_Alkylation_Strategy_for_the_Synthesis_of_Pyrano_3_4_i_b_i_indoles/2625826
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资源简介：
The synthesis of pyrano[3,4-b]indoles is described. The reaction sequence involves Sonogashira coupling of dihydropyran propargyl ether scaffolds with iodoanilines to afford intermediate indoles. Lewis acid-catalyzed ionization of the dihydropyrans, followed by intramolecular C3 alkylation of the indole, provides the title compounds.
创建时间：
2016-02-23
