Neuronal transcriptomic alterations in bifenthrin-exposed juvenile rainbow trout

An increased use of pyrethroid insecticides have been applied to the environment following the phase-out of organochlorines. A frequently identified pyrethroid in surface waters and sediment samples, bifenthrin, is of increasing concern to aquatic organisms, particularly salmonid species. To better characterize the neurotoxicity of bifenthrin to salmonids, juvenile rainbow trout were exposed to concentrations of bifenthrin commonly measured within the Sacramento-San Joaquin Delta for a two-week-long waterborne exposure and assessed for transcriptomic alterations to the brain and associated histopathological effects.