Oncogenic ETS proteins replace activated Ras/MAPK signaling in prostate cells.

ChEBI2011-10-19 更新2026-07-21 收录

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MAPK/ETS分子机制

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-29808 数据链接链接失效反馈

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Oncogenic ETS proteins replace activated Ras/MAPK signaling in prostate cells.

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2011-10-19

From HER2/Neu signal cascade to androgen receptor and its coactivators: A novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells

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受体调控

Overexpression of the HER2/Neu protooncogene has been linked to the progression of breast cancer. Here we demonstrate that the growth of prostate cancer LNCaP cells can also be increased by the stable

PubMed Central1999-05-11 更新60

Figure S1 - Functional Domains of Androgen Receptor Coactivator p44/Mep50/WDR77and Its Interaction with Smad1

蛋白质相互作用

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The interaction among AR, p44, Smad1 was detected by Co-immunoprecipitation in C4-2B cells. AR-p44-Smad1 is in an endogenous complex. (PPT)

NIAID Data Ecosystem40

Supplementary Table 2 from Hierarchical Phosphorylation of HOXB13 by mTOR Dictates Its Activity and Oncogenic Function in Prostate Cancer

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基因表达调控

Supplementary Table 2. RNA-seq analysis of LNCaP mTOR KD cells rescued with mTOR or empty vector (EV) control ± R1881 for 24h.

Figshare2023-07-26 更新30

Analysis of transcription regulation using KeyMolnet Lite; The top 8 transcription factors are located downstream from Pin1 in LNCap.

转录因子调控

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Analysis of transcription regulation using KeyMolnet Lite; The top 8 transcription factors are located downstream from Pin1 in LNCap.

NIAID Data Ecosystem50

Treatment of LNCaP prostate cancer cells with EGF and NRG

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基因表达谱分析

Gene expression signatures are routinely used to infer pathway activity. In this project, we stimulated LNCaP prostate cancer cells with growth factors to derive gene expression sigantures indicative

NIAID Data Ecosystem30

Oncogenic ETS proteins replace activated Ras/MAPK signaling in prostate cells.

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