Specific families of pattern recognition receptors are responsible for detecting microbial pathogens and generating innate immune responses. Toll-like receptors (TLRs) are membrane-bound receptors ide
Interleukin-7 (IL-7) was discovered in the year 1988 as a factor that enhanced the growth of murine B-cell precursors in bone marrow culture system. It was also known as lymphopoietin 1and pre-B cell
The table shows top three GO biological processes that have the highest overlap with each of the ten most frequently perturbed gene sets (in Table 1). The -value indicates the statistical significance
The recently identified type III interferon group consists of three IFN-λ (lambda) genes encoding molecules called IFN-λ1, IFN-λ2 and IFN-λ3 (also called IL29, IL28A and IL28B respectively). These IFN