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Cellular and molecular characterization of the altered metabolism in RCC

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE65168
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RCC cells (786-O) were transfected with VHL. The parental cell line should be compared to the transfectant (+ VHL) under nomoxia as well as under hypoxia conditions. We want to distinct the VHL-mediated gene expression from the hypoxia-mediated and study the influence of both on the cellular metabolism. RNA of VHL-negative 786-O RCC cell line and VHL-transfectants incubated during normoxia and hypoxia conditions were analysed by cDNA microarray.
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2018-07-26
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