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Crystal structure of the heterocyclic toxin methyltransferase from Mycobacterium tuberculosis with bound substrate 4-hydroxyisoquinolin-1(2H)-one

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Protein Data Bank Japan2025-12-10 更新2026-05-23 收录
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Crystal structure of the heterocyclic toxin methyltransferase from Mycobacterium tuberculosis with bound substrate 4-hydroxyisoquinolin-1(2H)-one Descriptor: 4-oxidanyl-2~{H}-isoquinolin-1-one, Heterocyclic toxin methyltransferase (Rv0560c), MALONATE ION, ... Authors: Denkhaus, L, Sartor, P, Einsle, O, Gerhardt, S, Fetzner, S. Deposit date: 2021-02-02 Release date: 2021-09-22 Last modified: 2025-12-10 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Structural basis of O-methylation of (2-heptyl-)1-hydroxyquinolin-4(1H)-one and related compounds by the heterocyclic toxin methyltransferase Rv0560c of Mycobacterium tuberculosis. J.Struct.Biol., 213, 2021

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2021-02-02
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