Additional file 2 of Five-year microevolution of a multidrug-resistant Mycobacterium tuberculosis strain within a patient with inadequate compliance to treatment
In Gram-negative bacteria, TEM-1 β-lactamase provides the major mechanism of plasmid-mediated β-lactam resistance. Natural variants of TEM-1 with increased antibiotic resistance have appeared in respo
Klebsiella spp. that secrete the DNA alkylating enterotoxin tilimycin colonize the human intestinal tract. Numbers of toxigenic bacteria increase during antibiotic use. The resulting accumulation of t
Fluoroquinolone antibiotics, a common antibiotic for the treatment of Pseudomonas aeruginosa infection, are facing challenges due to the rapid evolution of bacterial resistance. Through designed evolu
