Summary of MA experiments. The two right-hand columns display the numbers of synonymous (Syn) and nonsynonymous (NSyn) base-pair substitutions (BPS) identified, respectively, while the mean and standard deviation of three replicates are presented. All strains except LQ had identical numbers of MA rounds among the three replicate MA lines, respectively. The column of Generations shows the number of elapsed generations estimated from the number of MA rounds and the recorded colony size of each round, while the mean and standard deviation of three replicates are presented. A list of all detected mutations and an extended table showing the number of intergenic BPS and short Indels are shown in S1 and S2 Tables, respectively.

Summary of MA experiments. The two right-hand columns display the numbers of synonymous (Syn) and nonsynonymous (NSyn) base-pair substitutions (BPS) identified, respectively, while the mean and standard deviation of three replicates are presented. All strains except LQ had identical numbers of MA rounds among the three replicate MA lines, respectively. The column of Generations shows the number of elapsed generations estimated from the number of MA rounds and the recorded colony size of each round, while the mean and standard deviation of three replicates are presented. A list of all detected mutations and an extended table showing the number of intergenic BPS and short Indels are shown in S1 and S2 Tables, respectively.