Nutrition to Relieve IBS symptoms by targeting the Microbiota

This trial is a double-blind, randomized, placebo-controlled trial with 70 IBS subjects, allocated to five parallel arms (n = 14 each arm). A four-week intervention with five parallel arms (four supplement groups and one placebo group), during which the study participants consume the respective supplement twice per day. The primary objective is to determine the bifidogenic effects of a 4-week intervention with one of four dietary supplements (Chondroitin sulfate, NOVELOSE? 3490, and Pea Fiber, and Lactium?) in IBS patients. The secondary objective is to determine the effects of the same intervention on fecal microbiota composition and SCFA concentration, IBS-related complaints, Quality of Life, and stool frequency and consistency in IBS patients