Comprehensive microbiome analysis of tonsillar crypts in IgA nephropathy

We investigated the relationship between IgA nephropathy and the bacterial flora in the tonsils by analyzing the composition of the bacterial community in the crypts of the tonsils of IgAN patients and compared it to those of recurrent tonsillitis patients without urine abnormalities and children with tonsillar hyperplasia by using a high-throughput multiplexed 16S ribosomal RNA gene sequencing method.