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Figure 3 – Source Data (release probability and vesicle organization in dmPFC synapses)

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Figshare2025-11-25 更新2026-04-28 收录
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https://figshare.com/articles/dataset/Figure_3_Source_Data_release_probability_and_vesicle_organization_in_dmPFC_synapses_/30691820
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This dataset contains the raw numerical values used to generate all panels of Figure 3, which examines short-term synaptic plasticity, release probability, and ultrastructural vesicle organization at excitatory synapses in the dmPFC following chronic NMDAR hypofunction.Included data:- Short-term plasticity measurements during evoked EPSCs at 10 Hz stimulation (Panels 3a–e), including peak amplitudes, paired-pulse ratios, and normalized responses.- Release parameter analysis during 33.33 Hz stimulus trains (Panels 3f–i), including cumulative peak amplitudes, refilling rate, readily releasable pool (RRP) size, and release probability (Pr).- Ultrastructural TEM measurements (Panels 3j–p), including presynaptic bouton area, synapse density, PSD length, vesicle counts binned by distance from the active zone, CDFs of vesicle distribution, and vesicle diameters.Structure:- Each worksheet corresponds to a panel.- All values represent unprocessed raw data directly used to generate the plots in the manuscript.This dataset enables full reproduction of the synaptic release and ultrastructural analyses presented in Figure 3.
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