Regulatory T (Treg) cells play central roles in maintaining immune homeostasis and self-tolerance. However, the molecular mechanisms underlying Treg cell homeostasis and suppressive function are still
RNAseq analysis of Ex vivo Treg cells were isolated from wild type or Nfkb2-/- mice. WT and Nfkb2-/- Tregs were isolated as described above from spleens of bi-parental bone marrow chimeras. Sorted cel
BackgroundCD4+CD25+FOXP3+ Regulatory T cells (Treg) play a central role in the immune balance to prevent autoimmune disease. One outstanding question is how Tregs suppress effector immune responses in
