Transcriptome changes after overexpression, knockdown and condItional knockout of UXT in mice

Ubiquitously expressed transcript (UXT) has been shown to play a role in regulating the process of autophagy. Here, we investigated roles of UXT in the innnate immune responses after overexpression, knockdown and condItional knockout of UXT in mice Total RNA in mouse MEF cells after overexpression and knockdown of UXT was isolated and sequenced by deep sequencing using Illumina HiSeq 2500; Total RNA in mouse BMDM cells of myeloid-cell-specific UXT conditional knockout mice was isolated and sequenced by deep sequencing using Illumina HiSeq 2500;