Photo-Induction and Automated Quantification of Reversible Mitochondrial Permeability Transition Pore Opening in Primary Mouse Myotubes

Opening of the mitochondrial permeability transition pore (mPTP) is involved in various cellular processes including apoptosis induction. Two distinct states of mPTP opening have been identified allowing the transfer of molecules with a molecular weight线粒体通透性转换孔（mPTP）的开启涉及多种细胞过程，包括凋亡诱导。已识别出mPTP开启的两种不同状态，允许多分子量（molecular weight）的分子转移。