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Data for Recirculating Intestinal IgA-producing cells Regulate Neuroinflammation via IL10

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NIAID Data Ecosystem2026-03-10 收录
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The data set shows a collection of 6-scale point scores for Experimental Autoimmune Encephalomyelitis (EAE) induce with MOG35-55 in WT C57BL6, BAFF-Tg and Plasma Cell deficient mice. We find that some PC in the CNS of mice with EAE originate in the gut and produce IgA. Removal of PB/PC resulted in exacerbated EAE that was normalized by the introduction of gut-derived IgA+ PC.
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2019-02-14
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