ChIP-chip profiling of human gammaH2AX spreading around DNA double strand breaks

ChEBI2010-04-20 更新2026-07-21 收录

DNA损伤修复

ChIP-chip技术

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MEXP-1769 数据链接链接失效反馈

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ChIP-chip profiling of human gammaH2AX spreading around DNA double strand breaks

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2010-04-20

Discovery of Isaindigotone Derivatives as Novel Bloom’s Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair

DNA损伤修复

抗癌药物设计

Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that

NIAID Data Ecosystem40

Oxidative DNA damage is important to the evolution of antibiotic resistance: evidence of mutation bias and its medicinal implications

细菌耐药性机制

DNA损伤修复

Several1 studies have revealed that the reactive oxygen species (ROS) induced by antibacterial stimulation accelerates the evolution of antibiotic resistance, which uncovered new links between oxygen

Figshare2016-01-18 更新20

Transcriptome analysis of IR-treated HL-60 cells (shCtrl and shPTIP)

DNA损伤修复

基因表达调控

To explore the underlying molecular mechanisms behind DNA damage repair, gene expression profiles of shCtrl- and shPTIP (#1 and #2)-transduced HL-60 cells at 0 min and 180 min after IR were examined b

NIAID Data Ecosystem10

Aminofluorene DNA adduct at the pre-insertion site of a DNA polymerase

DNA损伤修复

跨损伤合成

Aminofluorene DNA adduct at the pre-insertion site of a DNA polymerase Descriptor: 2-AMINOFLUORENE, DNA polymerase I, DNA primer strand, ... Authors: Hsu, G.W, Kiefer, J.R, Becherel, O.J, Fuchs, R.P.P

Protein Data Bank Japan2023-08-23 更新30

p38-MK2 regulate RNA metabolism after UV light-induced DNA damage

DNA损伤修复

转录调控

Ultraviolet (UV) light induces the formation of bulky UV photoproducts in the genome that interfere with DNA replication and transcription. It is well-established how human cells repair UV light-induc

NIAID Data Ecosystem20

ChIP-chip profiling of human gammaH2AX spreading around DNA double strand breaks

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