The clinical characteristics and family cancer history for HBOC individuals analysed in the SNP array with the six validated copy number variations.

*Homozygous CNV.Abbreviations: BCC = Basal-cell carsinoma; Bil. Br = bilateral breast; Br = breast; Ca = cancer; Cer = cervix in situ carsinoma/cervix carsinoma; Co = colon; Dg = diagnosis; Del = deletion; Duct = ductal; Dup = duplication; Eso = esophagus; GI = gastrointestinal; gr = grade; Int = intestine; Kid = kidney; Lob = lobular; Mel = melanoma; na = not available; Ov = ovary; Panc = pancreatic; Sto = stomach; Thy = thyroid; To = tongue; Ute = ute. Cancers diagnosed in the paternal side of the family are presented in italics. Cancers diagnosed in siblings or their children of the index patients are underlined. Cancers diagnosed in the children of the index patients are presented in bold.