Adjusted risk ratio’s (yRiR) per year for the time trends in proportion of Escherichia coli and Klebsiella pneumoniae isolates resistant to third generation cephalosporins per patient setting, ISIS-AR, The Netherlands, 2008–2012.

aAdjusted risk ratio’s (yRiR) and 95% confidence intervals (95% CI) are generated with a log-binomial regression, adjusted patient characteristics, including age, gender and geographic region, and corrected for repeated measures using generalized estimating equation (GEE).The patient settings are: General Practitioner (GP), Outpatient Department (OPD), Inpatient Department (IPD) and Intensive Care Unit (ICU)b Because the absence of blood samples from GPs and the low number of isolates from OPD and IPD this both hospital locations were combined.Adjusted risk ratio’s (yRiR) per year for the time trends in proportion of Escherichia coli and Klebsiella pneumoniae isolates resistant to third generation cephalosporins per patient setting, ISIS-AR, The Netherlands, 2008–2012.