CDK9/cyclin T1 in complex with KB-0742

CDK9/cyclin T1 in complex with KB-0742 Descriptor: (1S,3S)-N3-(5-pentan-3-ylpyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine, Cyclin-T1, Cyclin-dependent kinase 9 Authors: Zhou, M, Li, H, Gao, H, Trotter, B.W, Freeman, D. Deposit date: 2023-07-24 Release date: 2023-12-06 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.751 Å) Cite: Discovery of KB-0742, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of CDK9 for MYC-Dependent Cancers. J.Med.Chem., 66, 2023