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Cu(I)-Catalyzed Asymmetric Multicomponent Cascade Inverse Electron-Demand Aza-Diels–Alder/Nucleophilic Addition/Ring-Opening Reaction Involving 2‑Methoxyfurans as Efficient Dienophiles

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Figshare2016-03-25 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Cu_I_Catalyzed_Asymmetric_Multicomponent_Cascade_Inverse_Electron_Demand_Aza_Diels_Alder_Nucleophilic_Addition_Ring_Opening_Reaction_Involving_2_Methoxyfurans_as_Efficient_Dienophiles/3119098
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资源简介:
An unprecedented multicomponent cascade asymmetric inverse-electron-demand Diels–Alder/nucleophilic addition/ring-opening reaction involving 2-methoxyfurans as efficient dienophiles was successfully developed with Cu­(I)/tBu-Box complex as the catalyst. A diverse array of tetrahydropyridazines containing unexpectedly stable γ-hydroxyl ester moiety was obtained in generally good yield with exclusive regioselectivity and excellent stereoselectivity.
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2016-03-25
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