Hypoxia and dimethyloxalylglycine (DMOG) downregulates tryptophan-2,3-dioxygenase (TDO2) expression in GBM cells
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE138535
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资源简介:
The tryptophan degrading enzyme TDO2 is downregulated upon HIF1alpha stabilization by exposure to both hypoxia as well as chemical hypoxia mimetics such as DMOG in glioblastoma cell line A172. Hypoxia: expression profile of A172 cells under hypoxic (1% oxygen) and normoxic (18.6% oxygen) conditions after 5 days (n = 5). DMOG: expression profile of A172 cells treated with 3mM dimethyloxalylglycine (DMOG) for 24 hours compared to EtOH control (n=3).
创建时间:
2019-12-29



