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Supplemental Table 1 from WTX-124, a Conditionally Activated Wild-Type IL2, Maximizes the Therapeutic Index of IL2, Unlike “Non-Alpha” Muteins

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NIAID Data Ecosystem2026-05-10 收录
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https://figshare.com/articles/dataset/Supplemental_Table_1_from_WTX-124_a_Conditionally_Activated_Wild-Type_IL2_Maximizes_the_Therapeutic_Index_of_IL2_Unlike_Non-Alpha_Muteins/31484116
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Tumors were implanted and INDUKINE treatment was performed as described in Figure 2. RNA from each tumor was isolated on day 5 and subjected to immune profiling with the NanoString nCounter PanCancer Mouse Immune Profiling panel. Table includes the Z scores of transcripts with statistically significant differences (p < 0.05) in expression between the vehicle group and either treatment group. Each column represents the gene expression profile of the tumor from an individual animal.
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2026-03-04
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