Highly Enantioselective Copper-Catalyzed Electrophilic Trifluoromethylation of β-Ketoesters
收藏NIAID Data Ecosystem2026-03-07 收录
下载链接：
https://figshare.com/articles/dataset/Highly_Enantioselective_Copper_Catalyzed_Electrophilic_Trifluoromethylation_of_Ketoesters/2508388
下载链接
链接失效反馈官方服务：
资源简介：
Enantioselective Cu-catalyzed trifluoromethylation of
β-ketoesters
using commercially available trifluoromethylating reagents is reported.
A number of α-CF3 β-ketoesters are obtained
with up to 99% ee. The trifluoromethylated products were then transformed
diastereoselectively to α-CF3 β-hydroxyesters
with two adjacent quaternary stereocenters via a Grignard reaction.
创建时间：
2016-02-20
