P1A4 Fab in complex with ARS1620
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P1A4 Fab in complex with ARS1620 Descriptor: (S)-1-{4-[6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl] piperazin-1-yl}propan-1-one, P1A4 Fab Heavy Chain, P1A4 Fab Light Chain, ... Authors: Basu, K, Rohweder, P.J, Zhang, Z, Bohn, M.-F, Shokat, K, Craik, C.S. Deposit date: 2020-10-27 Release date: 2022-04-27 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2 Å) Cite: A covalent inhibitor of K-Ras(G12C) induces MHC class I presentation of haptenated peptide neoepitopes targetable by immunotherapy. Cancer Cell, 40, 2022
创建时间：
2020-10-27
