Precision Imaging Essential Tremor (PIET) dataset

Dataset description:Participants. A total of 45 ET patients (mean age = 62.02 ± 13.10 years, 15 females) were recruited from HPPH, China. The inclusion criteria included being aged 22 years or above and a confirmed diagnosis of ET. Exclusion criteria comprised the following: (a) MRI contraindications; (b) presence of any other neurodegenerative disease, such as Parkinson-plus syndromes; and (c) a history of neuropsychiatric disorders aside from ET, including stroke, cerebrovascular disease, seizures, and psychosis.MRI acquisition. Participants underwent one structural MRI scan lasting 8 minutes and 50 seconds, and five  scans, each spanning 6 minutes and 14 seconds, resulting in a cumulative scan duration of 31 minutes and 10 seconds. MRI was performed using a Siemens 3T Prisma MRI scanner equipped with a 64-channel head coil. The structural scans involved T1-weighted images acquired through a MP2RAGE sequence (TI1 = 755 ms, TI2 = 2500 ms, TE = 3.43 ms, TR = 5,000 ms, flip angle1 = 4°, flip angle2 = 5°, matrix size = 256 ×256, 208 sagittal slices, spatial resolution = 1 × 1 × 1 mm3). An acceleration factor of 3 (with 32 reference lines) was applied in the primary phase encoding direction, with online GRAPPA image reconstruction. RsfMRI data were acquired using a gradient-echo echo planar imaging (GE-EPI) sequence (TE = 35 ms, TR = 2,000 ms, flip angle = 80º, and 75 slices, spatial resolution = 2.2 × 2.2 × 2.2 mm3). During data acquisition, participants were instructed to maintain their eyes open, remain awake while keeping their body still, and minimize head movement.