Transcriptome sequencing for cancer stem cell properties in MCF-7 cells with knocked down CD24
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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CD24 is the one of cell surface protein that anchored via glycosyl phosphatidylinositol that links to cell surface and modulates growth and differentiation signal many of cell types. A small population of cells, namely âCancer Stem Cells (CSCs)â, charges highly aggressive and metastatic character of cancer cells and shows conformational change of âepithelial to mesenchymal transition (EMT). To understand the role of CD24 in CSC and EMT, CD24 was knocked down using siRNA in the MCF7 cell line (MCF-7 hCD24 KD) and analyzed transcriptome profiles by mRNA-sequencing. Corresponding author: Chul Geun Kim, Department of Life Science, Hanyang University, Seoul 133-791, Korea (e-mail, cgkim@hanyang.ac.kr).
提供机构：
NAR Center, Inc. & Genoplan, Inc.
创建时间：
2022-02-20
