five

IRAK4 in complex with AZ3862

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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IRAK4 in complex with AZ3862 Descriptor: (3~{a}~{S},7~{a}~{R})-1-methyl-5-[4-[[5-(oxan-4-yl)-7~{H}-pyrrolo[2,3-d]pyrimidin-4-yl]amino]cyclohexyl]-3,3~{a},4,6,7,7~{a}-hexahydropyrrolo[3,2-c]pyridin-2-one, Interleukin-1 receptor-associated kinase 4, SULFATE ION Authors: Ferguson, A.D. Deposit date: 2016-05-26 Release date: 2017-12-06 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.23 Å) Cite: Discovery and Optimization of Pyrrolopyrimidine Inhibitors of Interleukin-1 Receptor Associated Kinase 4 (IRAK4) for the Treatment of Mutant MYD88L265P Diffuse Large B-Cell Lymphoma. J. Med. Chem., 60, 2017
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2016-05-26
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