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mitoTev‐TALE: a monomeric DNA editing enzyme to reduce mutant mitochondrial DNA levels

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HRA Figshare2026-03-16 更新2026-07-03 收录
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This work describes the development of a mitochondrial‐targeted DNA editing enzyme that can specifically cleave the MERRF m.8344A>G mtDNA mutation. The novel feature of this enzyme is that it is monomeric, in contrast to mitoTALEN and mitoZFN, which are heterodimeric.

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HRA Figshare
创建时间:
2019-04-07
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