Estrogen Drives Melanocortin Signaling to Increase Spontaneous Activity. Estrogen Drives Melanocortin Signaling to Increase Spontaneous Activity

Transcriptional profilig of estradiol sensitive genes in the VMHvl of female mice Overall design: For the vehicle treatment condtion, 3 biological replicates were analyzed. In the estradiol benzoated (EB) treated group, 4 biological replicates were analyzed. In both cases, each biological replicate represents material isolated from a single mouse. Please note that the mice are on a mixed background (as they are originally derived from the floxed Esr1 line generated in Sohaib Khan's lab, PMID: 17785410, and therefore come from a 129/Sv lineage).