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Crystal structure of a pyrazolopyrimidine inhibitor complex bound to MAPKAP Kinase-2 (MK2)

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Protein Data Bank Japan2023-11-01 更新2026-03-21 收录
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Crystal structure of a pyrazolopyrimidine inhibitor complex bound to MAPKAP Kinase-2 (MK2) Descriptor: MAP kinase-activated protein kinase 2, N~7~-(4-ethoxyphenyl)-6-methyl-N~5~-[(3S)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine, SULFATE ION Authors: Fujino, A, Takimoto-Kamimura, M. Deposit date: 2009-05-12 Release date: 2010-05-12 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural analysis of an MK2-inhibitor complex: insight into the regulation of the secondary structure of the Gly-rich loop by TEI-I01800 Acta Crystallogr.,Sect.D, 66, 2010

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2009-05-12
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