Plasma proteomic analysis of systemic lupus erythematosus patients using liquid chromatography/tandem mass spectrometry with label-free quantification

This is a comparative proteomic analysis study to identify the differentially expressed proteins from systemic lupus erythematosus patients. The plasma samples of SLE were compared with healthy controls using mass spectrometry analysis followed by label-free quantification. A total of 19 differentially expressed proteins were identified from SLE and these play important roles in inflammation, complement activation and acute phase responses of SLE.